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Antibacterial Activity Test of Mahkota Dewa Fruit (Phaleria macrocarpa) Extract against Escherichia Coli Bacteria
Exposure to Escherichia coli during pregnancy may cause serious
problems such as anemia, premature birth and an increased risk of
inflammation of the lining of the brain in the fetus. Mahkota Dewa
(Phaleria macrocarpa) is a medicinal plant that is widely known and
used to treat allergies and chronic diseases. One of the compounds
contained in Mahkota Dewa is flavonoids. There is certain
mechanism of action of flavonoids in inhibiting bacteria namely by
damaging the cytoplasmic cell wall in bacteria. This study aims to
analyze the antibacterial properties of various flavonoid
concentrations of Mahkota Dewa fruit (Phaleria macrocarpa) extract
against Escherichia coli bacteria through a laboratory experimental
study design by testing the antimicrobial potency of the well method,
namely 10%, 20%, 40%, 60%, 80% and 100%. Statistical analysis
using One-Way Anova Test showed a significant difference between
changes in the concentration of flavonoids in Mahkota Dewa fruit
extract and the inhibition zones towards the growth of Escherichia
coli bacteria (p
EJN000089 | 618.2 RET a | Perpustakaan Universitas Nurul Jadid | Tersedia namun tidak untuk dipinjamkan - Koleksi Digital |
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